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Which of the following microbial recognition receptors mediates cytokine production and induces an adaptive immune response?

Question and options

Which of the following microbial recognition receptors mediates cytokine production and induces an adaptive immune response?
  1. Toll-like receptor
  2. CD14
  3. Mannose receptor
  4. Scavenger receptor

Answer and explanation

Correct answer: A - Toll-like receptor
Toll-like receptors recognise microbial patterns and signal (via NF-kB) to produce cytokines and costimulatory molecules that trigger adaptive immunity; CD14, mannose and scavenger receptors mainly mediate binding/phagocytosis.

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