Which among the following is a characteristic of an autosomal recessive genetic disorder?
Question and options
Which among the following is a characteristic of an autosomal recessive genetic disorder?
- Affected individuals typically have unaffected parents
- The disorder is more common in males than females
- Only one copy of the mutant allele is needed for the disorder to manifest
- The disorder is often associated with advanced maternal age
Answer and explanation
Correct answer: A - Affected individuals typically have unaffected parents
In autosomal recessive disorders affected individuals typically have unaffected heterozygous (carrier) parents. Needing only one mutant copy describes dominant inheritance, male excess describes X-linked traits, and advanced maternal age describes nondisjunction disorders.
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