Site navigation

Tay-Sachs disease is due to the deficiency of

Question and options

Tay-Sachs disease is due to the deficiency of
  1. Hexosaminidase A
  2. α\alpha Galactosidase A
  3. Arylsulfatase A
  4. Hexosaminidase B

Answer and explanation

Correct answer: A - Hexosaminidase A
Tay-Sachs disease results from deficiency of hexosaminidase A, causing GM2\mathrm{G_{M2}} ganglioside accumulation. Deficiency of alpha-galactosidase A causes Fabry disease and deficiency of arylsulfatase A causes metachromatic leukodystrophy.

Practice for these exams

  • CUSAT CAT M.Sc. Forensic Science

  • Bihar Judicial Services

    Subject revision

  • Uttarakhand Judicial Services

    Subject revision

Related question papers

Related exam syllabi

More solved explanations in General science & technology