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Pick the wrong statement regarding DNA and RNA.

Question and options

Pick the wrong statement regarding DNA and RNA.
  1. DNA has higher molecular mass than RNA
  2. DNA being double helical is less stable than RNA
  3. Nucleotides in both RNA and DNA are joined together through phosphodiester linkages to form polynucleotides
  4. RNA has uracil as one among the bases whereas DNA has thymine as one among the bases

Answer and explanation

Correct answer: B - DNA being double helical is less stable than RNA
The statement 'DNA being double helical is less stable than RNA' is wrong: DNA is more stable than RNA because it lacks the 2'-OH group that makes RNA prone to hydrolysis and is stabilised by its double-stranded helix. The other three statements (higher molecular mass of DNA, phosphodiester linkages between nucleotides forming polynucleotides, and uracil in RNA versus thymine in DNA) are correct.

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