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Glycolysis will be adversely affected if …………… is inactivated.

Question and options

Glycolysis will be adversely affected if …………… is inactivated.
  1. Ligases
  2. Phosphofructokinase
  3. Glucose-6-phosphate phosphatases
  4. Pyruvate dehydrogenase

Answer and explanation

Correct answer: B - Phosphofructokinase
Phosphofructokinase-1 catalyses the committed, rate-limiting step of glycolysis, so inactivating it blocks glycolysis. Pyruvate dehydrogenase acts after glycolysis, and glucose-6-phosphatase works in gluconeogenesis.

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